![]() The HR for a subsequent CRBSI was 14% lower in a replaced than in a retained CVC (95% CI: 0.74, 0.99). The overall risk of CRBSI relapse was 7.5%, and the risk of CRBSI recurrence was 7.3%. The mean ± SD salvage rate was 55.3% ± 5.5%, varying according to infection type and causative microorganism. There were 2006 tunneled CVCs inserted in 715 adult HPS patients covering 2014.3 CVC years, with a CRBSI incidence rate of 1.83/1000 (n = 1350) and a mortality rate of 0.007/1000 CVC days (n = 5). Cumulative incidence curves are presented with a competing risk model. Cox regression analyses incorporated a frailty factor to account for recurrent events and overrepresentation by some patients. Re-occurrences of CRBSIs with the same microbial species and identical antibiogram were defined as a relapse (<30 d) or as a recurrent (30–100 d) infection. Catheter salvage was defined by successful antimicrobial therapy with a retained CVC at discharge. All CRBSIs from 2002 to 2016 in the Copenhagen IF and microbiological databases were retrospectively analyzed. ![]() ![]() This observational study investigated the consequences of a catheter-salvage strategy related to CRBSIs. In intestinal failure (IF) patients receiving home parenteral support (HPS), catheter-related bloodstream infections (CRBSIs) frequently result in replacement of their tunneled central venous catheters (CVCs), which may lead to future loss of central venous access. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |